CD3 anticorps (FITC)

N° du produit ABIN487431

Cet anticorps anti-CD3 est un anticorps Hamster Monoclonal détectant CD3 dans FACS. Adapté pour Souris.

Aperçu rapide pour CD3 anticorps (FITC) (ABIN487431)

Antigène: CD3

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: 145-2C11

Détail du produit anti-CD3 anticorps (FITC)

Specificité: This antibody reacts with mouse CD3 (epsilon subunit). It is commonly used as a phenotypic marker for mouse T cells.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Attributs du produit: Synonyms: T3/Leu-4, T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4

Immunogène: Mouse BM10-37 cytotoxic T lymphocytes

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry: Use 2 μg/mL dilution as recommended startingpoint for use of this product.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, approx. pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD3

Antigène: CD3

Autre désignation: CD3

Sujet: CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

ID gène: 12501

UniProt: P22646

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway